An undated photo of Nancy Guthrie and Savannah Guthrie was provided by NBC in response to the disappearance of the 84-year-old mother of the “Today” show host. (Courtesy of NBC)
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Five pieces of evidence. No arrests. No named suspects.
As the disappearance of Nancy Guthrie enters its third week, investigators say the case remains wide open — but the trail of clues is growing more complex, and more unsettling, by the day.

Federal authorities comb store records and video in the Nancy Guthrie case, with former FBI agent Jason Pack explaining how retail forensics builds cases. (FBI, Derek Shook for Fox News Digital)
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The 84-year-old mother of Savannah Guthrie vanished from her Tucson home in the Catalina Foothills during the early hours of February 1. From the outset, authorities have treated the property as a crime scene, with Federal Bureau of Investigation now offering a $100,000 reward for information leading to answers.

An exterior view of the front entrance of Nancy Guthrie’s home in Tucson, Arizona, on Tuesday, February 3, 2026. (Derek Shook for Fox News Digital)
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Here are the five key pieces of evidence investigators are focusing on so far.

1. The Timeline That Changed Everything

According to Pima County Sheriff Chris Nanos, Nancy Guthrie ate dinner with relatives on January 31 and was dropped home at 9:48 p.m. Her garage door closed two minutes later.

At 1:47 a.m., her Nest doorbell camera went offline.
At 2:28 a.m., her pacemaker lost connection with her smartphone.
By midday on February 1, she was officially reported missing.

An FBI billboard in Albuquerque, N.M., has raised raising awareness about the search for missing Nancy Guthrie. (KRQE)
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Authorities believe she was removed from her home against her will during this window.

2. The Masked Figure on Video

Recovered footage from Guthrie’s Nest camera shows a masked man at her door, carrying a stuffed backpack and what appears to be a holstered firearm.

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FBI analysts estimate the individual stands between 5ft 9in and 5ft 10in, with a medium build. The backpack has been identified as a black Ozark Trail model, sold at Walmart for around $11. The holster is believed to be a Strategy brand hip holster, also commonly sold at Walmart.

3. The DNA Discovery

Investigators recovered DNA from an unknown individual inside the home — not matching Guthrie, family members, or household workers.

Sixteen gloves were later found within a two-mile radius of the property. One glove, believed to match the one seen in the surveillance video, contained an unknown male DNA profile. Authorities planned to compare it against federal databases, though results have not been publicly confirmed.

4. Blood at the Front Door

A trail of blood droplets on the front steps has been confirmed as Nancy Guthrie’s.

Sheriff Nanos has declined to say whether the blood was present before or after she was taken and has refused to discuss additional forensic findings from inside the home, citing the ongoing investigation.

5. The Pacemaker Search — And Digital Forensics

Guthrie’s pacemaker provided a crucial timestamp when it disconnected from her phone. Hoping it could offer more, authorities deployed advanced Bluetooth signal-scanning equipment by air — but the search yielded no results.

Behind the scenes, investigators are also analyzing roadside cameras, home surveillance footage, cell-tower data, and other digital records. Thousands of tips have been submitted, and residents within a two-mile radius have been asked to provide any video recorded between January 1 and February 2.

An undisclosed tip recently led to a late-night search of a nearby home and vehicle, along with the temporary detention of three people. None were charged, and no suspects have been named.

A Case Still Without Answers

Despite intense scrutiny, national attention, and cutting-edge forensic tools, Nancy Guthrie’s fate remains unknown. Authorities insist they are following every lead — both public and private — and say even the smallest detail could break the case open.

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Anyone with information is urged to contact the FBI at 1-800-CALL-FBI.